phenytoin will reduce the extent or influence of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
Geriatric Use In aged patients, it is suggested the dosage be restricted to the smallest successful total to preclude the development of ataxia or oversedation (two mg to two.5 mg a few times day-to-day, in the beginning to be enhanced step by step as needed and tolerated).
eslicarbazepine acetate will minimize the extent or outcome of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
Suggest patients to stop driving or working large machinery until patient is mindful of the results of your drug
iloperidone raises levels of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on. Iloperidone is really a time-dependent CYP3A inhibitor and will lead to improved plasma amounts of drugs predominantly removed by CYP3A4.
acetazolamide will raise the degree or effect of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Unknown.
Antegrade amnesia may perhaps come about employing therapeutic dosages, the risk expanding at increased dosages. Amnestic effects may very well be linked to inappropriate actions.
Reports of sedation, very poor feeding and weak excess weight obtain in infants exposed to diazepam by means of breast milk; there won't be any data on outcomes of diazepam on milk generation
Reserve concomitant prescribing of these drugs in patients for whom other remedy selections are insufficient. Limit dosages and durations on the minimal expected. Observe intently for indications of respiratory despair and sedation.
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voriconazole will increase the amount or influence of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
Limit dosage and period if concomitantly applied; observe carefully for respiratory melancholy and sedation
dasatinib will enhance the amount or result of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
Watch Intently (one)belzutifan will minimize the level or effect of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism.